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CHC We also found a significantly inverse
2020-05-09

We also found a significantly inverse correlation of OPRM1 CpG2-4 methylation level with HDL-C in Han male controls. Lipids are known to involve the inflammation pathway, Aβ formation and stability of neuron, whereby their abnormalities have been shown to increase the risk of AD [39], [40], [41]. HD
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Table presents results for estimation of Eq using
2020-05-09

Table 4 presents results for estimation of Eq. (1) using ACTR and SUWE to compare the incidence of attempting the exam between programs. We find alumni are more likely to attempt the exam if they GSA 10 do not hold another professional certification, have worked for an accounting firm, have a highe
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br Introduction Schistosomiasis one of the major parasitic d
2020-05-08

Introduction Schistosomiasis, one of the major parasitic diseases that affect humans in tropical and subtropical countries, is an acute and chronic condition caused by blood flukes (trematode worms) of the genus Schistosoma (World Health Organization, 2014). Schistosomiasis infects over 240 milli
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In cancer interactions between the
2020-05-08

In cancer, interactions between the transformed cancer jnk pathway and other cell types recruited to the tumor are important. Tumor associated macrophages provide cancer cells with a suitable low-grade inflammatory milieu including growth promoting factors. Our results suggest a novel pro-tumorigen
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The mutation in Caucasian people of European heritage is
2020-05-08

The Δ32 mutation in Caucasian people of European heritage is quite common but extremely rare in Asian and African countries (Huang et al., 1996). We recently reported the presence of this mutation from India (Husain et al., 1998a) and established the complete inheritance pattern (Husain et al., 1998
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br Acknowledgments We thank the Lapaha Community
2020-05-08

Acknowledgments We thank the Lapaha Community and Nobles (His Serene Highness Prince Kalaniuvalu Fotofili, Her Serene Highness Princess Marcella Taumoepeau Tupou Kalaniuvalu Fotofili and Her Royal Highness Mele Siu\'ilikutapu Kalaniuvalu Fotofili) and the Ministry of Internal Affairs (Government
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Replacement of the saturated propoxy group
2020-05-08

Replacement of the saturated -propoxy group in compound with the unsaturated allyloxy group to obtain compound resulted in 10-fold decrease in ET receptor antagonism and more than 20-fold decrease in ET-selectivity. Analogous unsaturated allyloxy compound in the tetrazole series was found to have
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br Compliance with ethical standards This
2020-05-07

Compliance with ethical standards This work was conducted in compliance with ethical standards. Conflict of interest Funding The work was funded by extra mural research grant (EMR/2016/005135) from Science and Engineering Research Board, Government of India. Acknowledgements Introduc
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NVP-ADW742 Studies of Jelski and Szmitkowski show that diffe
2020-05-07

Studies of Jelski and Szmitkowski show that differences of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity between NVP-ADW742 of many cancers and healthy tissue may be one of the factors intensifying carcinogenesis [7]. Moreover, changes of ADH and ALDH activity in cancer cel
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The phenotypes of KD Ddr transgenic mice
2020-05-07

The phenotypes of KD-Ddr2 transgenic mice were less severe than expected from the results of miDdr2-transfected ATDC5 cells, which indicated that DDR2 might play important roles in endochondral ossification but neither critical nor essential roles in determining total body and skeleton size. The gr
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br Materials and methods br Results br Discussion The main
2020-05-07

Materials and methods Results Discussion The main finding of the present study is that selective ETA and dual ETA/ETB receptor blockade markedly improve endothelium-dependent vasodilatation in patients with type 2 diabetes and vascular complications. The magnitude of improvement did not dif
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Natural progestogens play an important role in the stimulati
2020-05-07

Natural progestogens play an important role in the stimulation of oocyte growth and maturation as well as in spermatogenesis and sperm maturation, and they act as sex pheromones in teleost fish (Kime, 1990, Kobayashi et al., 2002, Nagahama and Yamashita, 2008, Scott et al., 2010). A complex series o
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The small intestine in addition to its primary
2020-05-06

The small intestine, in addition to its primary role of absorption, has the ability to metabolize drugs and other xenobiotics through phase 1 and phase 11 metabolisms [25] since almost all the cytochrome P450 notch pathway present in the liver are also present in the small intestine although, in lo
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In the present work we have
2020-05-06

In the present work, we have investigated the reactivity of N-aryl-N′-hydroxyguanidines 1a–d (see Scheme 1 for structures) with the water-soluble Cu(II) complex 8. Using EPR and UV–Visible spectroscopy, we have shown that the studied N-aryl-N′-hydroxyguanidines 1a–d can bind and transfer electrons t
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br Experiments and Methods br Results
2020-05-06

Experiments and Methods Results and Discussion Conclusions Here, the interactions between two newly-synthesized carbazole derivative—cationic δ,δ′‑diazacarbazoles and DNA were characterized by several spectroscopic means, including UV–Vis and fluorescence, AFM and fluorescence imaging. The
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