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Since BM impairs the balance between bone formation
2019-05-08

Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re
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The gallstone Lith gene map
2019-05-08

The gallstone (Lith) gene map has been updated, which lists all known genetic loci that confer gallstone susceptibility, as well as candidate genes in inbred strains of mice. Understanding molecular genetics of gallstone disease in mice will push for the identification of human Lith genes. In additi
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The Cl HCO anion exchanger
2019-05-08

The Cl−/HCO3− anion exchanger 2 (AE2) is found on cholangiocytes and regulates intracellular pH homeostasis and stimulates bicarbonate secretion. Previous reports have revealed that PBC patients show decreased biliary AE2 expression, and researchers hypothesized that this decrease in AE2 etc may be
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Having to seek various approvals with no communication betwe
2019-05-08

Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen
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What can be done to reduce morbidity and
2019-05-08

What can be done to reduce morbidity and mortality in HEU infants? Notably, a third of all mortality in the Botswana trial occurred early, before randomisation. Similarly, in a trial of more than 14 110 infants in Zimbabwe, done in the pre-MTCT-prevention era, HIV-exposed uninfected infants had 50%
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br Discussion We herein report a case of
2019-05-08

Discussion We herein report a case of inappropriate shock therapy that was caused by T-wave oversensing and that occurred when the patient had sinus tachycardia and was squatting. Several methods were considered to troubleshoot this problem. We decreased the sensitivity and increased the NID and
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The effects of zoledronic acid are
2019-05-08

The effects of zoledronic hiv protease inhibitors are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal
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One of the lessons the
2019-05-07

One of the lessons the global health angiotensin receptor blocker learned from its experience with HIV was the need to rapidly identify individuals who are eligible for treatment. Yet HCV is severely underdiagnosed ( Lancet Glob Health —The following sentence should have read “Alarmingly, almost h
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Leptin synthesized in adipocytes is
2019-05-07

Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates
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br Conclusions The experimental results in isolated sheep he
2019-05-07

Conclusions The experimental results in isolated sheep hearts presented herein clearly demonstrate that self-sustained rotors exist in the atria. Such rotors are the high frequency sources that give rise to the complex patterns of activation that characterize AF. More specifically, our results su
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Reviewing the literature we knew that in cases of
2019-05-07

Reviewing the literature, we knew that in cases of AA, use of IST should be cautious, as IST might accelerate occult lymphoma escaping immune surveillance and evolving as a refractory lymphoma. Second, in cases of AA and concomitant NHL, to choose cytotoxic chemotherapy or IST is an art. Depending o
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br Material and methods br Results br
2019-05-07

Material and methods Results Discussion Conclusion Financial support Conflicts of interest Introduction Metabolic syndrome comprises a cluster of conditions, including obesity, insulin resistance, hypertension, and abnormal cholesterol levels, which together increase cardiovascu
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La cita anterior bien puede ser emblem tica del
2019-05-07

La cita anterior bien puede ser emblemática del presente estudio: en cuatro líneas, dentro del texto que recupera sus palabras y las une con las de Juan José Saer, Piglia asume que el proceso creativo de su poética, construida pathway lo largo de más de cinco décadas, tiene un signo dual que, por un
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Apesar de certo consenso em rela o necessidade de
2019-05-07

Apesar de certo consenso em relação à necessidade de construir táticas políticas, é preciso lembrar que boa parte das igrejas (neo) pentecostais foram elaboradas e se mantém com uma wee1 organizacional diferente da estrutura centralizada e verticalizada da iurd. A estrutura organizacional nestes mo
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br Methods br Discussion We observed a significantly lower
2019-05-07

Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial ochratoxin a had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progression remain
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